Thioridazine-induced diarrhoea

Electron microscopic observation of thioridazine-induced hepatitis.

The introduction of new drugs for clinical practice in recent years, has caused an increasing number of drug-induced hepatic injuries, which are currently receiving much attention because of their iatrogenic nature . As one of the approaches to the study of pathogenesis, electron microscopic studies have been undertaken. This report is concerned with an electron microscopic observation of the l...

Mycophenolate induced diarrhoea.

Mycophenolate (MMF) has arisen as an important addition in the immunosuppression armamentarium. GI disturbances (diarrhea) and bone marrow suppression are its main side effects requiring dose reduction or even withdrawal. The mechanism of diarrhoea is unknown, although some theories have been postulated. We evaluated three of our patients on MMF who came to us with chronic diarhoea. Their evalu...

Bile Acid Induced Diarrhoea

Thioridazine hydrochloride

Major uses Thioridazine hydrochloride (further thioridazine) is a representative of phenothiazine compounds, and it is an antipsychotic drug (synthesized in 1959). It relieves tension and anxiety, and acts against multiple symptoms, e.g. agitation, depression, behavior problems and sleep disturbances. Thioridazine is also effective in controlling the symptoms of schizophrenia, mania, and other ...

Cardiac Action Potential Prolongation Induced by Isolated Thioridazine Enantiomers